In this article, the importance of interdisciplinary ideas for modelling and understanding signal propagation in nerve fibres is described as a fascinating problem of biophysics. A mathematical model involves the physical laws, assumptions, hypotheses, and finally, the governing equations. The analysis of this complex process is at the interface of physics, chemistry, and mathematics, together with experimental studies in electrophysiology. It is stressed that the mindsets of different communities may hinder cooperation.
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